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edited by Anita Payne, Matthew Hardy and Lonnie Russell This volume presents an up-to-date compilation of information on the development, structure and function of the cell that produces testosterone. The Leydig Cell is invaluable for serious researchers and students of male reproductive physiology. Topics covered range from the identification of the cell by Franz Leydig in 1850 to current efforts targeting the Leydig cell as a means of achieving male contraception.
Table of Contents:
Foreword by David
M. de Kretser
Structure and Development
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10.
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Regulation of Leydig Cell Cholesterol Transport |
231-240
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| D. A. Freeman and F. F. G. Rommerts | ||
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11.
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Acute Regulation of Leydig Cell Steroidogenesis |
241-258
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| D. M. Stocco | ||
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12.
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Structure, Function and Regualtion of Steroidgenic Enzymes in the Leydig Cell |
259-286
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| A. H. Payne and P. J. O'Shaughnessy | ||
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13.
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Metabolism of Testosterone in Leydig Cells and Peripheral Tissues |
287-306
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| K. Sundaram and N. Kumar | ||
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14.
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Endocrinology of Leydig Cells in Nonmammalian Vertebrates |
307-332
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| G. B. Callard |
Regulation by Luteinizing Hormone
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15.
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The Luteinizing Hormone Receptor |
333-350
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| M. L. Dufau | ||
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16.
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Transduction of the Luteinizing Hormone Signal Within the Leydig Cell |
351-364
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| B. A. Cooke | ||
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17.
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Ontogeny of the Luteinizing Hormone Action in the Male |
365-382
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| I. Huhtaniemi |
Regulation By Factors Other Than Luteinizing Hormone
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18.
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Regulation of Leydig Cell Functions by Hormones and Growth Factors Other Than LH and IGF-1 |
383-406
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| J. M. Saez and H. Lejeune | ||
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19.
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Leydig Cell Regulation by Catecholamines and Neuroendocrine Messengers |
407-418
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| A. Mayerhofer |
Color Section
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20.
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Leydig Cell Structure and Function in Seasonal Breeders |
431-450
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| A. Bartke, A. P. Sinha Hikim and L. D. Russell | ||
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21.
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Leydig Cell-Macrophage Interactions: An Overview |
451-466
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| D. B. Hales | ||
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22.
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Leydig Cell-Sertoli Cell Interaction |
467-476
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| S. R. Sylvester | ||
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23.
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Insulin-Like Growth Factor-I Regualtion of the Leydig Cell |
477-492
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| T. Lin | ||
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24.
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Regulation of Leydig Cells by Inhibins and Activins |
493-506
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| G. P. Risbridger |
Physiological, Pathological and Clinical Aspects of Leydig Cells
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25.
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Fluid Exchange and Transport of Endocrine and Paracrine Solutes Supporting the Leydig Cell |
507-522
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| C. Desjardins | ||
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26.
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Immortalized Leydig Cell Lines as Models for Studying Leydig Cell Physiology |
523-534
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| S. R. Hoelscher and M. Ascoli | ||
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27.
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Leydig Cell Responsiveness to Hormonal and Nonhormonal Factors In Vivo and In Vitro |
535-554
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| G. R. Klinefelter and W. R. Kelce | ||
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28.
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Leydig Cell Neoplasia |
555-572
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| R. A. Huseby | ||
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29.
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Leydig Cell Toxicology |
573-596
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| I. D. Morris | ||
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30.
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Pharmacologic Influence on Angrogen Biosynthesis |
597-628
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| V. Papadopoulos | ||
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31.
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The Leydig Cell as a Target for Male Contraception |
629-662
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| G. F. Weinbauer and E. Nieschlag | ||
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32.
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Clinical Evaluation of Leydig Cell Function |
663-694
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| R. S. Swerdloff and C. Wang | ||
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33.
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Involvement of Leydig Cell Function in Precocious Puberty |
695-702
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| J. Z. Kasa-Vubu | ||
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34.
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Conditions Affecting Leydig Cells |
703-734
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| S. M. L. C. Mendis-Handagama |
Appendices I. Bibliographic Information
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